Developer Tools

Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

Provides guidance for LLM post-training with RL using slime, a Megatron+SGLang framework. Use when training GLM models, implementing custom data generation workflows, or needing tight Megatron-LM integration for RL scaling.

draw.io diagram creation, editing, and review. Use for .drawio XML editing, PNG conversion, layout adjustment, and AWS icon usage.

Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.

Production-ready patterns for building LLM applications. Covers RAG pipelines, agent architectures, prompt IDEs, and LLMOps monitoring. Use when designing AI applications, implementing RAG, building agents, or setting up LLM observability.

Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology images, detecting tissue regions, segmenting tissue masks, or preparing datasets for computational pathology deep learning pipelines. Applies to WSI formats (SVS, TIFF, NDPI), tile-based analysis, and histological image preprocessing workflows.

Python development principles and decision-making. Framework selection, async patterns, type hints, project structure. Teaches thinking, not copying.

Senior Quality Manager Responsible Person (QMR) for HealthTech and MedTech companies. Provides overall quality system responsibility, regulatory compliance oversight, management accountability, and strategic quality leadership. Use for quality system governance, regulatory compliance oversight, management responsibility, and quality strategic planning.

Expert patterns for Shopify app development including Remix/React Router apps, embedded apps with App Bridge, webhook handling, GraphQL Admin API, Polaris components, billing, and app extensions. Use when: shopify app, shopify, embedded app, polaris, app bridge.

Create and edit Obsidian Bases (.base files) with views, filters, formulas, and summaries. Use when working with .base files, creating database-like views of notes, or when the user mentions Bases, table views, card views, filters, or formulas in Obsidian.

Create publication figures with matplotlib/seaborn/plotly. Multi-panel layouts, error bars, significance markers, colorblind-safe, export PDF/EPS/TIFF, for journal-ready scientific plots.